PATHOMORPHOLOGICAL AND IMMUNOHISTOLOGICAL CHARACTERISTICS OF REGULAR LYMPH NODES IN COVID-19
Keywords:
COVID-19, lymph nodes, pathomorphology, immunohistology, SARS-CoV-2, immune response, germinal center hyperplasia, inflammatory markers, autopsy, biopsyAbstract
this article examines the pathomorphological and immunohistological characteristics of regular lymph nodes in patients diagnosed with COVID-19. Using comprehensive analysis of lymphoid tissue obtained from autopsy and biopsy, the study aimed to identify morphological changes and immune response patterns associated with SARS-CoV-2 infection. The findings reveal significant changes in lymph node architecture, including hyperplasia of germinal centers and changes in lymphocyte populations that indicate a robust immune response. In addition, immunohistochemical staining showed increased inflammatory markers. This study provides valuable insights into the immune landscape associated with COVID-19 and its implications for understanding disease progression and potential therapeutic targets.
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