QANDLI DIABETDA QON TOMIRLARINING GISTOLOGIK O'ZGARISHLARI
Keywords:
qandli diabet, qon tomirlari, gistologik o'zgarishlar, mikroangiopatiya, endoteliy, bazal membranaAbstract
Ushbu maqolada qandli diabetda qon tomirlarida yuzaga keladigan asosiy gistologik o'zgarishlar tahlil qilindi. Giperglikemiya, oksidlovchi stress, glikatsiyalangan yakuniy mahsulotlar va surunkali yallig'lanish endoteliy disfunktsiyasini kuchaytirib, bazal membrananing qalinlashishi, peritsitlar kamayishi, gialinoz, aterosklerotik shikastlanish va mikroangiopatiyani yuzaga keltirishi ko'rsatildi. Keltirilgan ma'lumotlar diabetik retinopatiya, nefropatiya, neyropatiya hamda makrovaskulyar asoratlarning morfologik asosini tushuntirishga xizmat qiladi.
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