STRESSNING BUYRAK USTI BEZI PO‘STLOG‘I HUJAYRALARIGA GISTOLOGIK TA’SIRI
Keywords:
Stress, buyrak usti bezi, po‘stloq qavat, zona fasciculata, kortizol, gistologiya, gipotalamus–gipofiz–buyrak usti tizimi, mitoxondriya, endoplazmatik to‘r, apoptozAbstract
Mazkur maqolada stressning buyrak usti bezi po‘stlog‘i hujayralariga ko‘rsatadigan gistologik va ultrastruktur ta’sirlari o‘rganilgan. Stress organizmda gipotalamus–gipofiz–buyrak usti bezi tizimini faollashtirib, kortikosteroid gormonlar ishlab chiqarilishini kuchaytiradi. Natijada po‘stloq qavat hujayralarida morfologik va funksional o‘zgarishlar yuzaga keladi. Tadqiqot davomida zona fasciculata hujayralarida silliq endoplazmatik to‘rning kengayishi, mitoxondriyalarning gipertrofiyasi, lipid tomchilarining kamayishi va sekretor faollikning ortishi aniqlangan. Surunkali stress davomida degenerativ va apoptotik o‘zgarishlar rivojlanishi kuzatilgan. Maqolada ushbu o‘zgarishlar gistologik va fiziologik nuqtai nazardan tahlil qilingan.
References
1. Junqueira L.C., Carneiro J. Basic Histology: Text and Atlas. McGraw-Hill Education, 2018.
2. Ross M.H., Pawlina W. Histology: A Text and Atlas. Wolters Kluwer, 2020.
3. Gartner L.P., Hiatt J.L. Color Atlas and Text of Histology. Lippincott Williams & Wilkins, 2017.
4. Guyton A.C., Hall J.E. Textbook of Medical Physiology. Elsevier, 2021.
5. Ganong W.F. Review of Medical Physiology. McGraw-Hill, 2019.
